Research Scientist, Cellular Pharmacology/Assay Development

Location: Cambridge, MA


Kronos Bio seeks a highly motivated Research Scientist to join its drug discovery team located in Cambridge, MA. As a member of an interdisciplinary team, this individual is expected to harness their substantial oncology background to generate important scientific data and help guide strategic scientific decisions and research program development. The applicant is expected to have a robust experimental skill-set, an eagerness for learning, and contribute to a strong culture of teamwork and collaboration in a fast-paced environment.


  • Coordinate with R&D team members to lead key elements of discovery and preclinical development programs for novel cancer therapies.
  • Design, develop and execute in vitro assays required for the advancement of high priority projects, including cell model development and engineering, cell-based bioassays and in vitro pharmacologic characterization (e.g. cell viability assays, qRT-PCR, western blot).
  • Experience with knockdown or over-expression techniques in in vitro models including CRISPR, shRNA, ASO or lentiviral overexpression to define gene expression programs.
  • Experience using laboratory automation and robotics is a plus.
  • Experience working closely with computational biologists and/or medicinal chemists is a plus.
  • Manage and direct external resources (CRO) and collaborators.
  • Present and discuss results with the Kronos Bio team and the external research community; work collaboratively with a team of talented scientists.
  • Demonstrated ability to thrive in a collaborative cross-functional team environment, self-motivated but team player.


  • PhD or MS/BS in Biology with 0 years (PhD) or 6 years (MS/BS) industry/biotech experience.
  • Ability to work independently and able to balance multiple tasks or projects.
  • Diligent with details and timely execution and delivery of high-quality results.
  • Strong background in basic research or translational research in oncology, including but not limited to high throughput screening, cell-based assays, molecular biology and protein chemistry.
  • Familiarity with analysis of genomic and gene expression data sets.
  • Experience working with CROs and/or compound management organizations preferred.
  • Highly analytical mind, attention to detail, organization skills, and rigorous experimental record keeping using an ELN system are critical.
  • Collaborative, proactive and optimistic personality.
  • Embodies Kronos values; exhibits high degree of integrity and professionalism when interacting with outside investigators and vendors.
  • Entrepreneurial and enjoys working in a fast-paced, creative and resourceful small company environment.

To apply for this position, please forward your resume and cover letter to